| 产品详情 |
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| Product Name | JH 295 |
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| Description | Irreversible Nek2 inhibitor (IC50=770 nM). Inhibits Nek2 via alkylation of residue Cys22. Displays 5-fold selectivity for Nek2 over Cdk1. Exhibits no significant effect on Aurora B or Plk1 kinases, bipolar spindle assembly or spindle assembly checkpoint. Cell permeable. Purity 98%. MW (observed): 320.35 |
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| Size | 2 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(3Z)-3-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methylene]-2,3-dihydro-2-oxo-1H-indol-5-yl]-2-propynamide |
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| Gene, Accession, CAS # | CAS: 1311143-71-1 |
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| Catalog # | 4322/2 |
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| Price | |
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| Order / More Info | JH 295 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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