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Product Name | Recombinant Human U1 small nuclear ribonucleoprotein A (SNRPA), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 57kDa. Partial: 8-278aa. N-terminal GST-tagged. Homo sapiens (Human). Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assbly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds st loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | n/a |
Gene, Accession, CAS # | SNRPA, UniProt: P09012 |
Catalog # | RPC23937 |
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Order / More Info | Recombinant Human U1 small nuclear ribonucleoprotein A (SNRPA), partial from BIOMATIK |
Product Specific References | n/a |
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