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| Product Name | (S)-Crizotinib |
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| Description | Potent MTH1 inhibitor (IC50 = 72 nM). Induces DNA damage and disrupts nucleotide pool homeostasis in cancer cells. Also attenuates colony formation of KRAS-mutated PANC1 cells in vitro. Suppresses tumor growth ~50% in a colon cancer carcinoma xenograft model. Purity 98%. MW (observed): 450.34 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine |
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| Gene, Accession, CAS # | CAS: 1374356-45-2 |
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| Catalog # | 6025/50 |
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| Price | |
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| Order / More Info | (S)-Crizotinib from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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