| 产品详情 |
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| Antigenic Specificity | BRCA1 |
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| Clone | BRCA1/1398 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | Protein A/G purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | FC, IF, IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Monoclonal antibody to detect BRCA1 in human samples. This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than |
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| Immunogen | Recombinant human BRCA1 protein fragment (aa445-620) |
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| Other Names | BRCA1, Breast and ovarian cancer susceptibility protein 1, Breast Cancer 1 Early Onset, Breast cancer type 1 susceptibility protein, BROVCA1, IRIS, PNCA4, PPP1R53, Protein phosphatase 1 regulatory subunit 53, PSCP, RING finger protein 53, RNF53 |
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| Gene, Accession # | Gene ID: 672, Accession: P38398 |
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| Catalog # | A1448-100 |
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| Price | |
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| Order / More Info | BRCA1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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