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Product Name | Recombinant Human CD59 glycoprotein (CD59) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 36kDa. Full Length of Mature Protein: 26-102aa. N-terminal GST-tagged. Homo sapiens (Human). Potent inhibitor of the complent mbrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complents of the assbling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complent binding activity, but exhibits greatly reduced ability to inhibit MAC assbly on cell mbranes. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | 1F5 antigen20KDA homologous restriction factor; HRF-20; HRF20MAC-inhibitory protein; MAC-IPMEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRLProtectin; CD59 |
Gene, Accession, CAS # | CD59, UniProt: P13987 |
Catalog # | RPC21062 |
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Order / More Info | Recombinant Human CD59 glycoprotein (CD59) from BIOMATIK |
Product Specific References | n/a |
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