| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | AKT1 |
|---|
| Clone | RM252 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG |
|---|
| Format | Protein A purified |
|---|
| Size | 50 µl |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit monoclonal antibody to detect Akt1 in human samples. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. They have a pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-? tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Phosphorylation of both residues is important to generate a high level of Akt1 ac |
|---|
| Immunogen | A synthetic peptide corresponding to the C-terminus of human Akt1 |
|---|
| Other Names | PKB, RAC, Protein kinase B, Protein kinase B alpha, Short PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase |
|---|
| Gene, Accession # | Gene ID: 207, Accession: P31749 |
|---|
| Catalog # | A1117-50 |
|---|
| Price | |
|---|
| Order / More Info | AKT1 Antibody from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|