| 产品详情 |
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| Product Name | GC 1 |
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| Description | Thyromimetic; high affinity agonist at thyroid hormone receptor (TR) β and TRα receptors (KD values are 67 and 440 pM respectively). Displays 5- and 100-fold greater potency than the endogenous agonist T3 in vitro at TRα1 and TRβ1 receptors respectively. Promotes reverse cholesterol transport in chow- and fat-fed mice. Induces proliferation of hepatocytes and pancreatic acinar cells in rats independent of prior tissue injury. Purity 98%. MW (observed): 328.4 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid. Sobetirome |
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| Gene, Accession, CAS # | CAS: 211110-63-3 |
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| Catalog # | 4554/10 |
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| Price | |
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| Order / More Info | GC 1 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 16006512, 27117475, 29175051 |
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