| 产品详情 |
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| Product Name | Dapagliflozin |
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| Description | A first generation, selective SGLT inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM; EC50 = 1.1 nM) over SGLT1 (Ki = 390 nM); 0.1 to 1.0 mg/kg increases urinary glucose excretion in both normal and diabetic rats, improves glucose tolerance in normal rats, and reduces hyperglycemia in Zucker diabetic fatty rats |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Na+ sodium glucose cotransporters sodium-glucose cotransporter SGLTs inhibitors inhibits inhibitions renal kidneys readsorptions insulin insulin-independent insulin-dependent alternatives blood levels concentrations types 2 II diabetes glomerular filtrates SGLT2 SGLT-2 S2 S1 segments proximal tubes tubular regions SGLT1 SGLT-1 1 readsorbs distal S3 small intestines first generations blocking blocks transports urine urinary excretions excretes normal diabetic rats tolerance hyperglycemia Zucker fatty fasting fasts fed selective productions metabolic syndromes metabolisms co-transporters co transporters |
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| Gene, Accession, CAS # | CAS: 461432-26-8 |
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| Catalog # | 11574-50 |
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| Order / More Info | Dapagliflozin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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