| 产品详情 |
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| Antigenic Specificity | COBRA1/NELFB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100ug |
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| Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for COBRA1 detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Cofactor of BRCA1, also known as COBRA1, is a human gene that encodes NELF-B. NELF-B is a subunit of negative elongation factor (NELF), which also includes NELF-A (WHSC2), either NELF-C or NELF-D (TH1L), and NELF-E (RDBP). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1) and SPT5 (SUPT5H), to cause transcriptional pausing of RNA polymerase II. COBRA1 was initially identified in a yeast two-hybrid screen using the BRCT1 domain of BRCA1 as bait. |
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| Immunogen | E. coli-derived human COBRA1 recombinant protein (Position: M1-E252). |
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| Other Names | Negative elongation factor B; NELF-B; Cofactor of BRCA1; NELFB; COBRA1; KIAA1182 |
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| Gene, Accession # | NELFB, UniProt: Q8WX92 |
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| Catalog # | A12025-1 |
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| Price | |
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| Order / More Info | COBRA1/NELFB Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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