| 产品详情 |
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| Antigenic Specificity | KDM1B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human. |
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| Isotype | n/a |
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| Format | serum |
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| Size | 50 µl |
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| Concentration | n/a |
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| Applications | ELISA. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal Antibody to detect KDM1B in human samples. KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. |
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| Immunogen | Polyclonal antibody raised in rabbit against human KDM1B (lysine (K)-specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N-terminal and the central region of the protein, respectively. |
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| Other Names | AOF1, LSD2, C6orf193 |
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| Gene, Accession # | Gene ID: 221656, Accession: Q8NB78 |
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| Catalog # | 6847-50 |
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| Price | |
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| Order / More Info | KDM1B Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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