| 产品详情 |
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| Antigenic Specificity | alpha Actinin |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | hamster, human, mouse, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:25, Immunofluorescence: 1:25, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | alpha Actinin Polyclonal Antibody. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar |
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| Immunogen | n/a |
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| Other Names | F-actin cross-linking protein; actinin 1 smooth muscle; alpha-actinin 1; alpha-actinin cytoskeletal isoform; alpha-actinin-1; non-muscle alpha-actinin-1 |
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| Gene, Accession # | Entrez: 100755831, 109711, 81634, 87; Uniprot: P12814, Q7TPR4, Q9Z1P2 |
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| Catalog # | PA5-17308 |
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| Price | |
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| Order / More Info | alpha Actinin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27035161, 29333637 |
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