| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | alpha Actinin 2/3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | alpha Actinin 2/3 Polyclonal Antibody. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. |
|---|
| Immunogen | n/a |
|---|
| Other Names | CMD1AA, F-actin cross-linking protein, alpha-actinin skeletal muscle, alpha-actinin-2, Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, ACTN3, alpha-Actinin3, Actinin alpha3, Actinin alpha3, alphaActinin-3, Actinin-alpha3, alpha-actinin-3 |
|---|
| Gene, Accession # | Entrez: 11472, 11474, 171009, 291245, 88, 89; Uniprot: O88990, P35609, Q08043, Q9JI91 |
|---|
| Catalog # | PA5-38605 |
|---|
| Price | |
|---|
| Order / More Info | alpha Actinin 2/3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|