| 产品详情 |
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| Antigenic Specificity | alpha Actinin 4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2-3 µg/mL, Immunofluorescence: 2-3 µg/mL, Western Blot: 2-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | alpha Actinin 4 Polyclonal Antibody. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involve |
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| Immunogen | n/a |
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| Other Names | ACTININ-4, FSGS, FSGS1, F-actin cross-linking protein, actinin alpha4 isoform, alpha-actinin-4, focal segmental glomerulosclerosis 1, non-muscle alpha-actinin 4 |
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| Gene, Accession # | Entrez: 60595, 63836, 81; Uniprot: O43707, P57780, Q9QXQ0 |
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| Catalog # | 42-1400 |
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| Price | |
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| Order / More Info | alpha Actinin 4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16944923, 20463653, 26936875 |
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