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| Product Name | Recombinant Human Collagenase 3 (MMP13) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 58.3kDa. Full Length of Mature Protein: 104-471aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Plays a role in the degradation of Extracellular domain matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue rodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal bryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Matrix metalloproteinase-13; MMP-13 |
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| Gene, Accession, CAS # | MMP13, UniProt: P45452 |
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| Catalog # | RPC21671 |
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| Order / More Info | Recombinant Human Collagenase 3 (MMP13) from BIOMATIK |
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| Product Specific References | n/a |
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