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| Product Name | G-1 |
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| Description | G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in endoplasmic reticulum α- (ERα-) and ERβ-expressing cells yielded Ki values for estradiol of 0.30 and 0.38 nM, respectively, with no substantial binding of G-1 at 1 µM.{14210} The discovery of G-1, a compound that does not bind classical ERs, should facilitate further physiological experiments to define the role of GPR30 in vivo. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GPR30 estrogen receptors ER ER.alpha. ER ER.beta. 17b-estradiol 17.beta.-estradiol 17beta-estradiol protein-coupled ERalpha ERbeta endoplasmic reticulum signaling agonists in vivo endocrinology |
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| Gene, Accession, CAS # | CAS: 881639-98-1 |
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| Catalog # | 10008933-10 |
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| Order / More Info | G-1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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