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| Product Name | CD154-muCD8-Biotin |
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| Description | Information: Human CD154 (CD40 Ligand) is a member of the tumor necrosis factor (TNF) family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function (1). CD154 has been shown to be hyperexpressed by B and T cells in SLE patients (4). CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells and |
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| Size | 0.025 mg |
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| Concentration | 0.5 mg/ml |
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| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB) |
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| Other Names | [Human CD154 (CD40 Ligand) muCD8/Biotin] |
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| Gene, Accession, CAS # | [CD154] |
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| Catalog # | MBS666788 |
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| Order / More Info | CD154-muCD8-Biotin from MYBIOSOURCE INC. |
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| Product Specific References | 1) D. Gray, et al, (1994) Seminars in Immunol 6: 303-310. 2) F. Pietravalle, et al, (1996) J Biol Chemistry 271: 5965-5967. 3) R.J. Noelle, (1996) Immunity 4: 415-419. 4) A. Desai-Mehta, et al, (1996) J Clin Invest 97: 2063-2073. 5) I.S. Grewal and R.A. Flavell, (1996) Immunol Today 17: 410-414. 6) F. Mach, et al, (1997) Proc Natl Acad Sci USA 94:1931-1936. |
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