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| Product Name | CD275-muIg-purified Preservative Free |
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| Description | Purified Preservative Free. Information: The inducible costimulator (ICOS, T cell activation molecule H4) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Unlike CD28, ICOS is only expressed on activated T cells. Secondary signaling through CD28 or ICOS results in discrete cytokine secretion profiles by the activated T cells(1). Engagement of CD152 (CTLA-4) anergizes cells costimulated with either CD28 and ICOS(2). Signaling through IC |
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| Size | 0.025 mg |
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| Concentration | 0.5 mg/ml |
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| Applications | Flow Cytometry (FC/FACS), ELISA (EIA) |
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| Other Names | [Human CD275(GL50, ICOS L)trn-muIg Fusion Protein] |
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| Gene, Accession, CAS # | [CD275] |
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| Catalog # | MBS666845 |
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| Order / More Info | CD275-muIg-purified Preservative Free from MYBIOSOURCE INC. |
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| Product Specific References | 1) Beier, K.C., R.A. Kroczek, et al. 2000, Eur J Immunol. 30(12):3707-3717. 2) Riley, J.L., C.H. June, et al. 2001, J. Immunol. 166: 4943-4948. 3) Ling, V., M. Collins, et al. 2000, J. Immunol. 164: 1653-1657. 4) Ling, V., M. Collins, et al. 2001, J. Immunol. 166: 7300-7308. 5) K.C. Beier, et al, (2000) Eur J Immunol 30: 3707-3717. 6) E. Ozkaynak, et al, (2001) Nat Immunol 2: 591-596. 7) J.B. Rottman, et al, (2001) Nat Immunol 2: 605-611. |
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