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Product Name | GalNAc-T2, soluble fragment, Human Recombinant |
Description | Polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty GalNAc-T genes have been identified in humans and most have been shown to represent active GalNAc-Ts. All isoforms are type II transmembrane proteins, with different but partly overlapping substrate preferences. The GalNAc-Ts control the initiation of mucin-type O-linked glycosylation and determine the location and density of O-glycans in a protein. Addition of GalNAc to an unglycosylated Ser/Thr residue creates the Tn antigen GalNAca1-S/T, and subsequent addition of sialic acid by ST6GalNAc-I forms the cancer associated STn antigen. GalNAc-T2 is p |
Size | 5 µg |
Concentration | 360 ug/ml |
Applications | RUO |
Other Names | Polypeptide N-acetylgalactosaminyltransferase 2, Polypeptide GalNAc transferase 2, GaNTase 2 |
Gene, Accession, CAS # | GALNT2, Gene ID: 2590, Accession: Q10471 |
Catalog # | P1215-5 |
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Order / More Info | GalNAc-T2, soluble fragment, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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