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| Product Name | GalNAc-T3, soluble fragment, Human Recombinant |
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| Description | Polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) catalyzes the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the hydroxyl group of serine and threonine residues. Twenty GalNAc-T genes have been identified in humans and most have been shown to represent active GalNAc-Ts. All isoforms are type II transmembrane proteins, with different but partly overlapping substrate preferences. The GalNAc-Ts control the initiation of mucin-type O-linked glycosylation and determine the location and density of O-glycans in a protein. Addition of GalNAc to an unglycosylated Ser/Thr residue creates the Tn antigen GalNAcα1-S/T, and subsequent addition of sialic acid by ST6GalNAc-I forms the cancer associated STn antigen. GalNAc-T |
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| Size | 5 µg |
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| Concentration | 466 ug/ml |
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| Applications | RUO |
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| Other Names | Polypeptide N-acetylgalactosaminyltransferase 3, Polypeptide GalNAc transferase 3, GaNTase 3 |
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| Gene, Accession, CAS # | GALNT3, Gene ID: 2591, Accession: Q14435 |
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| Catalog # | P1216-5 |
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| Order / More Info | GalNAc-T3, soluble fragment, Human Recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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