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| Product Name | Human PKR Synthetic Peptide |
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| Description | Human PKR Synthetic Peptide. PKR is a 68 kDa protein and an IFN-induced serine/threonine protein kinase consisting of two N-terminal RNA-binding regulatory domains and a functional C-terminal serine/threonine protein kinase domain. Activated by dsRNA produced during viral infections, PKR plays a key role in IFN induced-innate antiviral response, virus-induced apoptosis, cell growth & differentiation. Upon activation, PKR gets autophosphorylated and catalyzes the phosphorylation of elF2 alpha subunit, which leads to an inhibition of protein synthesis. PKR induces apoptosis by up-regulating Fas expression and mediates FADD/Caspase-8 death signaling pathway. Upon viral infection, it functions as a dual protein, sequentially activating both cel |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 5610; Uniprot: P19525 |
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| Catalog # | PEP-0417 |
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| Order / More Info | Human PKR Synthetic Peptide from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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