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| Product Name | Recombinant Human C-X-C motif chemokine 3 protein (CXCL3) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 15.26kDa. Full Length of Mature Protein: 24-155aa. tag-Free. Homo sapiens (Human). Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; IL17A; CTLA8; IL17 |
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| Gene, Accession, CAS # | IL17A, UniProt: Q16552 |
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| Catalog # | RPC26879 |
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| Order / More Info | Recombinant Human C-X-C motif chemokine 3 protein (CXCL3) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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