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| Product Name | Recombinant Human C-X-C motif chemokine 5 protein (CXCL5) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE. MW: 16.9kDa. Partial: 34-179aa. tag-Free. Homo sapiens (Human). Interleukin-22 (IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by cytokine IL-17A. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Interleukin-22; IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL22; ILTIF; ZCYTO18 |
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| Gene, Accession, CAS # | IL22, UniProt: Q9GZX6 |
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| Catalog # | RPC26882 |
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| Order / More Info | Recombinant Human C-X-C motif chemokine 5 protein (CXCL5) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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