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Product Name | Recombinant Human C-X-C motif chemokine 9 protein (CXCL9) (Active) |
Description | Purity > 95% as determined by SDS-PAGE. MW: 12.5kDa. Full Length of Mature Protein: 49-162aa. tag-Free. Homo sapiens (Human). Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15. |
Size | n/a |
Concentration | n/a |
Applications | RUO |
Other Names | Interleukin-15; IL-15; IL15 |
Gene, Accession, CAS # | IL15, UniProt: P40933 |
Catalog # | RPC26885 |
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Order / More Info | Recombinant Human C-X-C motif chemokine 9 protein (CXCL9) (Active) from BIOMATIK |
Product Specific References | n/a |
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