| 产品详情 |
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| Product Name | Ribociclib (LEE011) |
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| Description | Ribociclib is a potent cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. LEE011 has been shown to reduce proliferation in 12 of 17 human neuroblastoma-derived cell lines by inducing cytostasis (mean IC50 = 306 nM in sensitive lines). MW: 434.54. Purity ≥98% by HPLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
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| Gene, Accession, CAS # | CAS: 1211441-98-3 |
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| Catalog # | 9481-25 |
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| Price | |
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| Order / More Info | Ribociclib (LEE011) from BIOVISION, INC. |
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| Product Specific References | n/a |
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