| 产品详情 |
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| Product Name | XMU-MP-1 |
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| Description | An inhibitor of MST1 and MST2 (IC50s = 71.1 and 38.1 nM, respectively); is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM; inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2 autophosphorylation in RAW 264.7, U2OS, SW480, RPE1, SNU423, and HepG2 cells in a concentration-dependent manner; prevents cell death induced by overexpression of MST2; enhances liver regeneration in mice post partial hepatectomy and reduces liver fibrosis in a mouse model of chronic liver injury when administered at a dose of 1 mg/kg, |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | XMUMP1 MP1 MST-1 2 MOB-1 LATS-1 2 Hep-G2 SNU-423 RPE-1 RAW264.7SW-480 |
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| Gene, Accession, CAS # | CAS: 2061980-01-4 |
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| Catalog # | 22083-5 |
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| Price | |
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| Order / More Info | XMU-MP-1 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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