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| Product Name | Recombinant Human Gap junction alpha-1 protein (GJA1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 20.3kDa. Cytoplasmic Domain: 233-382aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Connexin-43; Cx43; Gap junction 43KDA heart protein |
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| Gene, Accession, CAS # | GJA1, UniProt: P17302 |
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| Catalog # | RPC25879 |
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| Order / More Info | Recombinant Human Gap junction alpha-1 protein (GJA1), partial from BIOMATIK |
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| Product Specific References | n/a |
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