| 产品详情 |
| Edit |   |
|---|
| Product Name | SP 600125 |
|---|
| Description | Selective JNK inhibitor. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 - 90 nM) with negligible activity at ERK2, p38β and a range of enzymes. Active in vivo. Exhibits reduced selectivity over other protein kinases under certain conditions. Protects renal tubular epithelial cells against ischemia/reperfusion-induced apoptosis. Prevents BMP9-induced osteogenic differentiation of MSCs. Essential component of medium for maintaining stem cells in naive pluripotent state. Available as part of the MAPK Inhibitor Tocriset™. Purity 98%. MW (observed): 220.23 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Anthra[1-9-cd]pyrazol-6(2H)-one |
|---|
| Gene, Accession, CAS # | CAS: 129-56-6 |
|---|
| Catalog # | 1496/10 |
|---|
| Price | |
|---|
| Order / More Info | SP 600125 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 12522004, 12832416, 12902401, 14657960, 15615716, 15635152, 15640157, 15687501, 16061660, 16397234, 16410804, 16547493, 16627622, 16674821, 16705092, 16723500, 17283097, 17513605, 17714751, 18053155, 18258605, 18270325, 18281687, 18337448, 18441092, 18443042, 18768402, 18852146, 19037093, 19371341, 19458229, 19523197, 19738058, 19828633, 19855432, 20144602, 20724703, 20852130, 21097523, 21440539, 21622856, 21738764, 21854542, 21859479, 21994479, 22003401, 22031657, 22220695, 22275752, 22415826, 22434859, 22808290, 23209658, 23398885, 23497702, 23666803, 23699517, 23832324, 23967228, 24172903, 24222778, 24227191, 24358263, 24558305, 24627558, 24684682, 24760984, 24813396, 24836538, 25030704, 25256260, 25260613, 25352952, 25398056, 25435694, 25548285, 25609842, 25993292, 25999956, 26075891, 26089912, 26162907, 26251761, 26271343, 26414859, 26464620, 26649302, 26667040, 26700939, 27520483, 27802323, 28145533, 28322749, 28442401, 28484457, 28683288, 29175508 |
|---|
| 产品资料 |
|
|