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Product Name | CHIR-98014 |
Description | Cell-permeable. CHIR-98014 is a potent, selective and ATP-competitive inhibitor of GSK3α and GSK3β (IC50 = 0.65 and 0.58 nM, respectively). In addition, CHIR-98014 displays 500 to greater than 1000-fold selectivity towards GSK3 than other protein kinases such as cdc2 and ERK2. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis. MW: 486.31. Purity >98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine; CT 98014 |
Gene, Accession, CAS # | CAS: 556813-39-9 |
Catalog # | 2595-5 |
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Order / More Info | CHIR-98014 from BIOVISION, INC. |
Product Specific References | n/a |
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