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| Product Name | CHIR 98014 |
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| Description | Highly potent and selective GSK-3 inhibitor (IC50 values are 0.58 and 0.65 nM for the β and α isoforms, respectively). Exhibits >500-fold selectivity for GSK-3β over a range of other kinases. Improves insulin sensitivity of muscle strips from diabetic rats in vitro and decreases insulin and glucose levels in the oral glucose tolerance test in vivo. Activates Wnt signaling in human adipose stem cells (hASC) and promotes the production of definitive endoderm. Has been used in protocols to derive epicardial cells from hPSCs. Purity 98%. MW (observed): 486.31 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-1-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine |
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| Gene, Accession, CAS # | CAS: 252935-94-7 |
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| Catalog # | 6695/25 |
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| Order / More Info | CHIR 98014 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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