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| Product Name | CHMFL-FLT3-122 |
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| Description | Potent and selective FLT3 inhibitor (IC50 = 40 nM). Exhibits >10-fold and 170-fold selectivity for FLT3 over BTK kinase and c-KIT kinase, respectively in vitro. Induces apoptosis by arresting cell cycle in G0/G1 phase in vitro. Suppresses tumor growth in an AML xenograft model. Modestly orally bioavailable. MW (observed): 471.55. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-(dimethylamino)-ethanone |
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| Gene, Accession, CAS # | CAS: 1839150-56-9 |
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| Catalog # | 5800/10 |
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| Price | |
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| Order / More Info | CHMFL-FLT3-122 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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