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| Product Name | Recombinant Human Cation-dependent mannose-6-phosphate receptor |
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| Description | 1-277. MW: 58.4kD. Purity >90% as determined by SDS-PAGE. Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
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| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [46 kDa mannose 6-phosphate receptor; MPR 46] |
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| Gene, Accession, CAS # | M6PR, Gene ID: 4074, Accession: NP_002346.1 |
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| Catalog # | MBS717288 |
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| Order / More Info | Recombinant Human Cation-dependent mannose-6-phosphate receptor from MYBIOSOURCE INC. |
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| Product Specific References | Cloning of a cDNA encoding the human cation-dependent mannose 6-phosphate-specific receptor.Pohlmann R., Nagel G., Schmidt B., Stein M., Lorkowski G., Krentler C., Cully J., Meyer H.E., Grzeschik K.H., Mersmann G., Hasilik A., von Figura K.Proc. Natl. Acad. Sci. U.S.A. 84:5575-5579(1987) Isolation and analysis of the human 46-kDa mannose 6-phosphate receptor gene.Klier H.J., von Figura K., Pohlmann R.Eur. J. Biochem. 197:23-28(1991) Complete sequencing and characterization of 21,243 full-length |
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