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| Product Name | Recombinant Human Prostaglandin E synthase 3 (PTGES3) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 21.2kDa. Full length: 1-160aa. N-terminal 10xHis-tagged. Homo sapiens (Human). Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cytosolic prostaglandin E2 synthase (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23) |
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| Gene, Accession, CAS # | PTGES3, UniProt: Q15185 |
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| Catalog # | RPC25676 |
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| Order / More Info | Recombinant Human Prostaglandin E synthase 3 (PTGES3) from BIOMATIK |
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| Product Specific References | n/a |
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