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| Product Name | CD59, Recombinant, Human, aa26-102, His-Tag (Glycoprotein) |
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| Description | Purity ~90% (SDS-PAGE). Potent inhibitor of the complent membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complents of the assbling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complent binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. Source: Recombinant protein corresponding to aa26-102 from human CD59, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~11kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1F5 antigen 20kD homologous restriction factor, HRF-20, HRF20MAC-inhibitory protein, MAC-IPMEM43 antigen, Membrane attack complex inhibition factor, MACIF Membrane inhibitor of reactive lysis, MIRL Protectin, CD59 |
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| Gene, Accession, CAS # | SwissProt: P13987 |
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| Catalog # | 372677 |
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| Order / More Info | CD59, Recombinant, Human, aa26-102, His-Tag (Glycoprotein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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