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| Antigenic Specificity | Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) |
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| Clone | 3B12 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. |
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| Immunogen | Purified recombinant fragment of human C-CBL expressed in E. coli. |
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| Other Names | 4732447J05Rik|Cbl-2|c-Cbl|cbl|C-CBL|CBL2|FRA11B|NSLL|RNF55|c-cbl-like|RGD1561386 |
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| Gene, Accession # | Gene ID: 867,12402 |
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| Catalog # | ABIN968993 |
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| Price | |
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| Order / More Info | Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 19546888, 19620960, 19571318 |
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