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| Product Name | TOPK, Unactive Recombinant protein |
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| Description | MW: ~68 kDa. Recombinant full-length human TOPK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: TOPK is a MAPK kinase that phosphorylates p38 MAPK and is activated in a cell-cycle-dependent manner in neuronal progenitor cells in vitro (1). Expression of TOPK is detected in male germ line progenitor cells, activated T-cells, and a variety of lymphomas and leukemias. In vitro studies have shown that activated TOPK phosphorylated p3 |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay, Western Blot (WB) |
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| Other Names | [PBK; SPK; Nori-3; FLJ14385] |
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| Gene, Accession, CAS # | TOPK, Gene ID: 55872, Accession: NP_060962.2 |
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| Catalog # | MBS515388 |
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| Order / More Info | TOPK, Unactive Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Matsumoto, S. et al: Characterization of a MAPKK-like protein kinase TOPK. Biochem Biophys Res Commun. 2004; 325: 997-1004. 2. Simons-Evelyn, M. et al: PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells. Blood Cells Mol Dis, 2001; 27: 825-829. |
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