| 产品详情 |
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| Antigenic Specificity | DR6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | FCM |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR6 Polyclonal Antibody. • Target Background: Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further |
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| Immunogen | KLH conjugated synthetic peptide derived from human DR6. Immunogen Range: 140-170/655 |
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| Other Names | DR6; CD358; BM-018; Tumor necrosis factor receptor superfamily member 21; Death receptor 6; TNFRSF21; UNQ437/PRO868 |
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| Gene, Accession # | Gene ID: 27242, SwissProt: O75509 |
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| Catalog # | bs-7678R |
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| Price | |
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| Order / More Info | DR6 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Strilic, Boris, et al.(2016) Nature. PubMed: 27487218 |
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