| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | DR3 |
|---|
| Clone | 11HCLC |
|---|
| Host Species | Recombinant Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | IgG |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | DR3 Antibody (11HCLC), ABfinity™ Rabbit Oligoclonal. DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of DR3/TNFRSF25 in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative s |
|---|
| Immunogen | n/a |
|---|
| Other Names | APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR, apoptosis inducing receptor, apoptosis-inducing receptor AIR, apoptosis-mediating receptor DR3, apoptosis-mediating receptor TRAMP, death domain receptor 3 soluble form, death receptor beta, lymphocyte-associated receptor of death, protein WSL-1, tumor necrosis f |
|---|
| Gene, Accession # | Entrez: 500592, 85030, 8718; Uniprot: Q93038 |
|---|
| Catalog # | 711309 |
|---|
| Price | |
|---|
| Order / More Info | DR3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|