| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | DR4 |
|---|
| Clone | DR-4-02 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | 0.1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: Assay Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | DR4 Monoclonal Antibody (DR-4-02), FITC. TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor). |
|---|
| Immunogen | n/a |
|---|
| Other Names | APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1 |
|---|
| Gene, Accession # | Entrez: 8797; Uniprot: O00220 |
|---|
| Catalog # | MA1-19757 |
|---|
| Price | |
|---|
| Order / More Info | DR4 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|