| 产品详情 |
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| Antigenic Specificity | DR6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DR6 Polyclonal Antibody. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. |
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| Immunogen | n/a |
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| Other Names | UNQ437/PRO868, BM-018, CD358, DR6; TNFR-related death receptor 6; death receptor 6; tumor necrosis factor receptor superfamily member 21 |
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| Gene, Accession # | Entrez: 27242; Uniprot: O75509 |
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| Catalog # | PA5-19930 |
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| Price | |
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| Order / More Info | DR6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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