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| Product Name | Recombinant Human Kit ligand |
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| Description | 26-189aa; Partial. MW: 45.85kD. Purity >90% as determined by SDS-PAGE. Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hatopoiesis, st cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activati |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mast cell growth factor; MGFStem cell factor; SCFc-Kit ligand] |
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| Gene, Accession, CAS # | KITLG, Gene ID: 4254, Accession: NP_000890.1 |
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| Catalog # | MBS961597 |
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| Order / More Info | Recombinant Human Kit ligand from MYBIOSOURCE INC. |
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| Product Specific References | Primary structure and functional expression of rat and human stem cell factor DNAs.Martin F.H., Suggs S.V., Langley K.E., Lu H.S., Ting J., Okino K.H., Morris C.F., McNiece I.K., Jacobsen F.W., Mendiaz E.A., Birkett N.C., Smith K.A., Johnson M.J., Parker V.P., Flores J.C., Patel A.C., Fisher E.F., Erjavec H.O., Herrera C.J., Wypych J., Sachdev R.K., Pope J.A., Leslie I., Wen D., Lin C.-H., Cupples R.L., Zsebo K.M.Cell 63:203-211(1990) Alternate splicing of mRNAs encoding human mast cell growth f |
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