| 产品详情 |
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| Product Name | Lovastatin |
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| Description | Purity ≥98% (HPLC). Statin compound. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Causes cell cycle arrest in G1 and G2/M phases through modulation of proteasome in cancer cell lines. Smooth muscle cell proliferation inhibitor. Apoptosis inducer. Anticancer compound. Anti-adhesive, immunomodulatory and anti-inflammatory compound. Stimulates bone formation. Increases cellular resistance to anticancer agents such as doxorubicin and etoposide. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection. Anti-hypertensive agent. Suppresses TNF-induced NF-kappaB activation. Modulates key cell signaling pathways, like Ras, MAPK and EGFR (modest). Synonyms: Mevilonin; MK-803; 6-α-Methylcompactin; BRN 3631989 |
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| Size | 5mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Mevilonin, MK-803, 6-alpha-Methylcompactin, BRN 3631989 |
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| Gene, Accession, CAS # | CAS: 75330-75-5 |
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| Catalog # | 45022 |
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| Price | |
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| Order / More Info | Lovastatin from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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