| Edit |   |
| Antigenic Specificity | Munc13-4 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 ug |
| Concentration | n/a |
| Applications | Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:16000, Western Blot: 1-3 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Munc13-4 Polyclonal Antibody. This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. |
| Immunogen | n/a |
| Other Names | UNC13D; Munc13-4 ; unc-13 homolog D (C. elegans) ; FHL3; HLH3; HPLH3; unc-13 homolog D |
| Gene, Accession # | Entrez: 201294; Uniprot: Q70J99 |
| Catalog # | PA5-18281 |
| Price | |
| Order / More Info | Munc13-4 Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |