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| Product Name | NSC 109555 ditosylate |
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| Description | Selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 μM). Inhibits histone H1 phosphorylation (IC50 = 0.24 μM) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo. Purity 98%. MW (observed): 752.86 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4,4'-diacetyldiphenylurea bis(guanylhydrazone) ditosylate. DDUG |
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| Gene, Accession, CAS # | CAS: 66748-43-4 |
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| Catalog # | 3034/50 |
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| Order / More Info | NSC 109555 ditosylate from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21680529, 23855452, 24247150 |
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