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| Product Name | NSC 146109 (hydrochloride) |
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| Description | An activator of p53; increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells; selective for p53, having no effect on p73 expression in HCT116 cells (2 µM); increases p53 expression, decreases expression of the p53 suppressor MDMX, and reduces viability in a panel of breast cancer cell lines (0.5 µM); reduces growth of AMC-HN9 HNC cells in vitro and in vivo when administered alone or in combination with cisplatin in a mouse xenograft model (70 mg/kg) |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | XI-011 |
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| Gene, Accession, CAS # | CAS: 59474-01-0 |
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| Catalog # | 16430-25 |
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| Order / More Info | NSC 146109 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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