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| Product Name | Recombinant Human PAPPA2 / Pappalysin 2 Protein (His tag) |
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| Description | MW: 92,136 Da. Purity >90 % as determined by SDS-PAGE. Background: Pappalysin-2/PAPP-A2 is the second member of the pappalysin family of metzincin superfamily, of which PAPP-A is the first member. There is no homology between the prepro-peptides of PAPP-A and PAPP-A2, but 46% of the residues of mature PAPP-A are also present in mature PAPP-A2. PAPP-A specifically cleaves insulin-like growth factor-binding protein (IGFBP)-4, one of six known modulators of IGF-I and -II, whereas PAPP-A2 specifical |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | The secreted recombinant human PAPPA2 consists of 1174 amino acids with the predicted molecular mass of 131 kDa. As a result of glycosylation, rhPAPPA2 migrates as an approximately 170-180 kDa band in SDS-PAGE under reducing conditions. |
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| Other Names | [RP4-774I24.1, PAPP-A2, PAPPE, PLAC3] |
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| Gene, Accession, CAS # | PAPPA2, Gene ID: 60676, Accession: NP_064714.2 |
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| Catalog # | MBS2546200 |
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| Order / More Info | Recombinant Human PAPPA2 / Pappalysin 2 Protein (His tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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