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| Product Name | BRAF, 432-766aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 40.6 kDa (360aa). Purity >80% by SDS-PAGE. BRAF belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase B-raf; B-RAF1; BRAF1; NS7; RAFB1] |
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| Gene, Accession, CAS # | BRAF, Gene ID: 673, Accession: NP_004324 |
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| Catalog # | MBS205852 |
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| Order / More Info | BRAF, 432-766aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Brennan D.F., et al. (2011) Nature 472:366-369 |
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