产品详情 |
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Product Name | TPEN |
Description | Heavy metal chelator. Reacts with both Zn-proteome and Zn-metallothionein (MT) in LLC-PK1 cells; acts as an intracellular chelator of proteomic Zn2+. Activity decreases intracellular zinc levels, and induces apoptosis in HeLa and cultured human retinal pigment epithelium (RPE) cells. Also inhibits RNA binding protein Lin28 (IC50 = 2.5 μM). Cell permeable. Purity 98%. MW (observed): 424.54 |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine |
Gene, Accession, CAS # | CAS: 16858-02-9 |
Catalog # | 4309/100 |
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Order / More Info | TPEN from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 29802294 |
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