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| Product Name | RepSox |
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| Description | Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 values are 4 and 23 nM for TGF-β type I receptor autophosphorylation and binding respectively). Selective for TGF-β type I receptor over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). Enhances the efficiency of cellular reprogramming; replaces Sox2 by inducing Nanog expression. Purity 99%. MW (observed): 287.32 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine. E-616452, SJN 2511, ALK5 Inhibitor II |
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| Gene, Accession, CAS # | CAS: 446859-33-2 |
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| Catalog # | 3742/50 |
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| Price | |
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| Order / More Info | RepSox from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23563587, 23576681, 26837596, 27320041 |
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| 产品资料 |
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