产品详情 |
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Antigenic Specificity | NTAL |
Clone | W15102A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-NTAL (LAT2). Non-T cell activation linker (NTAL) functions as transmembrane adaptor scaffold that links engagement of antigen receptor binding to downstream effector molecules, playing an essential role in maturation, activation, and differentiation in various cell types. It is important for BCR (B-cell antigen receptor) and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-signaling in B-cells and myeloid cells, respectively, and plays a critical role in FCER1 (high affinity immunoglobulin epsilon receptor) signaling in mast cells. NTAL is encoded by the LAT2 gene, which is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome. |
Immunogen | Partial human NTAL recombinant protein (27-243 a.a.) expressed in E. coli. |
Other Names | NTAL, LAT2, WBS15, LAB |
Gene, Accession # | Gene ID: 7462 |
Catalog # | 699005 |
Price | |
Order / More Info | NTAL Antibody from BIOLEGEND |
Product Specific References | n/a |
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