| 产品详情 |
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| Product Name | Lactacystin |
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| Description | A cell-permeable, potent and selective proteasome inhibitor. A Streptomyces metabolite that is thought to bind irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2a neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-κB activation (IC50 = 10 μM). MW (observed): 376.42. |
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| Size | 200 ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester |
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| Gene, Accession, CAS # | CAS: 133343-34-7 |
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| Catalog # | 2267/200U |
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| Order / More Info | Lactacystin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21829588, 23303053, 24845182, 26295339 |
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| 产品资料 |
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